Pancreatic most cancers is at the moment probably the most deadly tumor entity and case numbers are rising. It’s going to quickly be the second most frequent explanation for most cancers-related dying within the Western world. Mortality is near incidence and affected person survival after prognosis stands at about 5 months. Blood-based diagnostics might be one essential issue for enhancing this dismal state of affairs and is at a stage that would make this attainable. Right here, we’re reviewing the present state of affairs with its issues and guarantees, varied molecule sorts.
Reported outcomes are evaluated within the total context. Additionally, we’re proposing steps towards scientific utility that ought to advance the event towards scientific software by enhancing biomarker high quality but in addition by defining distinct scientific goals and the respective diagnostic accuracies required to realize them. Lots of the mentioned factors and conclusions are extremely related to different stable tumors, too. Glia maturation factor-γ (GMFG) is reported to inhibit the actin nucleation by binding to the actin-related protein-2/Three advanced (Arp2/3).
Contemplating the primary operate of GMFG in actin transforming, which is significant for immune response, angiogenesis, cell division and motility, GMFG is meant to have essential roles in tumor growth, whereas thus far, solely two research described the position of GMFG in most cancerss. By investigating the scientific values of GMFG utilizing The Most cancers Genome Atlas (TCGA) knowledge and the practical mechanisms of GMFG by analyses of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichments, this examine was aimed to higher perceive the influence of GMFG in pan-most cancerss and to attract extra attentions for the longer term analysis of GMFG.
An asymptomatic 68-year-old girl who offered with an remoted hypercalcaemia was recognized with a uncommon, beforehand unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an intensive operation together with vascular resection and reconstruction, leading to profitable removing of the tumour with destructive margins. Medical and surgical administration of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is mentioned.
Domestically Superior Pancreatic Most cancers: Percutaneous Administration Utilizing Ablation, Brachytherapy, Intra-arterial Chemotherapy, and Intra-tumoral Immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) is without doubt one of the most aggressive neoplasms, bearing a horrible prognosis. Stage III tumors, also referred to as regionally superior pancreatic most cancers (LAPC), are unresectable, and present palliative chemotherapy regimens have solely modestly improved survival in these sufferers. At this stage of illness, interventional strategies could also be of worth and additional lengthen life. The intention of this evaluate was to discover present literature on locoregional percutaneous administration for LAPC.
Locoregional percutaneous interventional strategies similar to ablation, brachytherapy, and intra-arterial chemotherapy possess cytoreductive talents and have the potential to extend survival. As well as, latest analysis demonstrates the immunomodulatory capacities of those therapies. This immune response could also be leveraged by combining the interventional strategies with intra-tumoral immunotherapy, probably making a sturdy anti-tumor impact. This multimodality therapy strategy is at the moment being examined in a number of ongoing scientific trials.
Nevertheless, definitive conclusions can solely be made when massive potential (randomized managed) trials affirm these outcomes. Sufferers with biliary obstruction attributable to adenocarcinoma of the pancreas head might require bile duct decompression to deal with symptomatic cholestasis and/or allow systemic chemotherapy. Endoscopic retrograde cholangiopancreatography (ERCP) with biliary stent placement is the popular intervention in such instances. The first intention of this examine was to find out what quantity of sufferers with surgically unresectable pancreatic adenocarcinoma endure ERCP and whether or not this proportion has modified over time.
High quality of life (QoL) is broadly recognized to be poor after whole pancreatectomy (TP) because of the lack of pancreatic operate and poor dietary standing, however potential research on modifications in QoL over time are missing. The intention of this examine was to prospectively consider the short- and long-term penalties of pancreatic exocrine insufficiency, modifications in dietary standing, and their related results on QoL after TP. Using sure interventional strategies seems to enhance survival in LAPC sufferers and may match synergistically when mixed with immunotherapy.
Liver metastases
Liver metastases are generally detected in a variety of malignancies together with colorectal most cancers (CRC), pancreatic most cancers, melanoma, lung most cancers and breast most cancers, though CRC is the commonest major most cancers that metastasizes to the liver. Interactions between tumour cells and the tumour microenvironment play an essential half within the engraftment, survival and development of the metastases. Numerous cells together with liver sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, parenchymal hepatocytes, dendritic cells, resident pure killer cells in addition to different immune cells similar to monocytes, macrophages and neutrophils are implicated in selling and sustaining metastases within the liver.
4 key phases (microvascular, pre-angiogenic, angiogenic and progress phases) have been recognized within the means of liver metastasis. Imaging modalities similar to ultrasonography, CT, MRI and PET scans are usually used for the prognosis of liver metastases. Surgical resection stays the primary probably healing therapy amongst sufferers with resectable liver metastases. The position of liver transplantation within the administration of liver metastasis stays controversial. Systemic therapies, newer biologic brokers (for instance, bevacizumab and cetuximab) and immunotherapeutic brokers have revolutionized the therapy choices for liver metastases.
 DiscoveryProbe? Cardiovascular-related Compounds Panel |
|
L1004-5 |
ApexBio |
5 mg/well |
EUR 3928.8 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to cardiovascular system, including angiotensin and thrombin etc. Facilitate your research towards the insights of vascular disease, stroke, wound repair and cancer etc. |
 DiscoveryProbe? Ubiquitination-related Compounds Panel |
|
L1019-5 |
ApexBio |
5 mg/well |
EUR 3400.8 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to ubiquitination, including autophagy, proteasome and p97 etc. Facilitate your research towards the insights of cancer, diabetes, neurodegenerative and cardiovascular diseases etc. |
 DiscoveryProbe? GPCR/G protein-related Compounds Panel |
|
L1009-5 |
ApexBio |
5 mg/well |
EUR 7242 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc. |
 DiscoveryProbe? Chromatin/Epigenetics-related Compounds Panel |
|
L1006-5 |
ApexBio |
5 mg/well |
EUR 11167.2 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to chromatin/epigenetics, including bromodomain, aurora kinase, JAK, PARP and Pim etc. |
 DiscoveryProbe? Microbiology & Virology-related Compounds Panel |
|
L1014-5 |
ApexBio |
5 mg/well |
EUR 6267.6 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to microbiology & virology, including CCR5, HSV and CMV etc. Facilitate your research towards the insights of infection, immune diseases and cancer etc. |
 DiscoveryProbe? Proteases/Proteasome-related Compounds Panel |
|
L1016-5 |
ApexBio |
5 mg/well |
EUR 10262.4 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to proteases/proteasome, including cathepsin, DUB and gamma secretaseand HCV protease etc. |
 DiscoveryProbe? Immunology/Inflammation-related Compounds Panel |
|
L1010-5 |
ApexBio |
5 mg/well |
EUR 3219.6 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to immunology/inflammation, including TLR, PLA2 and NF-?B etc. Facilitate your research towards the insights of cancer, inflammatory and autoimmune diseases etc. |
 DiscoveryProbe? Cell Cycle/Checkpoint-related Compounds Panel |
|
L1005-5 |
ApexBio |
5 mg/well |
EUR 7548 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to cell cycle/checkpoint, including Chk, CDK and Plk etc. Facilitate your research towards the insights of DNA replication, tumorgenesis and aging etc. |
 DiscoveryProbe? DNA Damage/DNA Repair-related Compounds Panel |
|
L1007-5 |
ApexBio |
5 mg/well |
EUR 7172.4 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to DNA damage/DNA repair, including ATM/ATR, HDAC, and topoisomerase etc. Facilitate your research towards the insights of cancer, genome instability and immune diseases etc. |
 DiscoveryProbe? MAPK Signaling Pathway Compounds Panel |
|
L1020-5 |
ApexBio |
5 mg/well |
EUR 5320.8 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets on the MAPK signaling pathway, including MEK1/2, p38 and Raf etc. Facilitate your research towards the insights of cell proliferation, differentiation, apoptosis and motility etc. |
 DiscoveryProbe? Tyrosine Kinase/Adaptors-related Compounds Panel |
|
L1018-5 |
ApexBio |
5 mg/well |
EUR 11668.8 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to tyrosine kinase/adaptors, including ALK, c-MET, VEGFR and Src etc. Facilitate your research towards the insights of cancer, immune response, growth and differentiation etc. |
 DiscoveryProbe? Endocrinology and Hormones-related Compounds Panel |
|
L1008-5 |
ApexBio |
5 mg/well |
EUR 2829.6 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to endocrinology and hormones, including androgen receptor, estrogen/progestogen receptor and RAAS etc. Facilitate your research towards the insights of diabetes, thyroid disorders and cancer etc. |
 DiscoveryProbe? JAK/STAT Signaling Pathway Compounds Panel |
|
L1011-5 |
ApexBio |
5 mg/well |
EUR 3247.2 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets on the JAK/STAT signaling pathway, including EGFR, JAK and STAT etc. Facilitate your research towards the insights of differentiations, apoptosis, immunity and tumorigenesis etc. |
 DiscoveryProbe? Membrane Transporter/Ion Channel-related Compounds Panel |
|
L1012-5 |
ApexBio |
5 mg/well |
EUR 3776.4 |
|
Description: A wide range of well-characterized bioactive molecules that covers various targets related to membrane transporter/ion channel, including ATPase, calcium channel and CFTR etc. Facilitate your research towards the insights of heart diseases, cystic fibrosis and immune disorders etc. |
 DiscoveryProbe? Anti-cancer Compound Library |
|
L1023-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 24363.6 |
DiscoveryProbe? Anti-cancer Compound Library |
|
L1023-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 43768.8 |
DiscoveryProbe? Anti-cancer Compound Library |
|
L1023-5 |
ApexBio |
5 mg/well |
EUR 56853.6 |
 DiscoveryProbe™ Anti-cancer Compound Library |
|
L1023-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 13970 |
|
Description: 1164 anti-cancer compounds |
 DiscoveryProbe™ Anti-cancer Compound Library Plus |
|
L1023P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 21380 |
|
Description: 2227 anti-cancer compounds |
DiscoveryProbe™ Anti-cancer Compound Library Plus |
|
L1023P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 26719 |
|
Description: 2227 anti-cancer compounds |
DiscoveryProbe™ Anti-cancer Compound Library Plus |
|
L1023P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 48049 |
|
Description: 2227 anti-cancer compounds |
 DiscoveryProbe? Metabolism-related Compound Library |
|
L1032-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 10291.2 |
DiscoveryProbe? Metabolism-related Compound Library |
|
L1032-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 18434.4 |
DiscoveryProbe? Metabolism-related Compound Library |
|
L1032-5 |
ApexBio |
5 mg/well |
EUR 24002.4 |
 DiscoveryProbe? GPCR Compound Library |
|
L1025-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 5683.2 |
DiscoveryProbe? GPCR Compound Library |
|
L1025-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 10221.6 |
DiscoveryProbe? GPCR Compound Library |
|
L1025-5 |
ApexBio |
5 mg/well |
EUR 13284 |
 DiscoveryProbe? Bioactive Compound Library |
|
L1022-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 28066.8 |
DiscoveryProbe? Bioactive Compound Library |
|
L1022-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 50450.4 |
DiscoveryProbe? Bioactive Compound Library |
|
L1022-5 |
ApexBio |
5 mg/well |
EUR 65623.2 |
 DiscoveryProbe™ GPCR Compound Library |
|
L1025-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 5418 |
|
Description: A unique collection of 931 GPCR-related small molecules for GPCR screening. |
 DiscoveryProbe™ Metabolism-related Compound Library |
|
L1032-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 5880 |
|
Description: A unique collection of 493 metabolism-related compounds for metabolism research. |
 DiscoveryProbe™ Bioactive Compound Library |
|
L1022-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 16100 |
|
Description: 3317 bioactive compounds |
 DiscoveryProbe? JAK/STAT Compound Library |
|
L1041-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 2704.8 |
DiscoveryProbe? JAK/STAT Compound Library |
|
L1041-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 4792.8 |
DiscoveryProbe? JAK/STAT Compound Library |
|
L1041-5 |
ApexBio |
5 mg/well |
EUR 6184.8 |
 DiscoveryProbe? Stem Cell Compound Library |
|
L1040-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 5223.6 |
DiscoveryProbe? Stem Cell Compound Library |
|
L1040-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 9386.4 |
DiscoveryProbe? Stem Cell Compound Library |
|
L1040-5 |
ApexBio |
5 mg/well |
EUR 12170.4 |
 DiscoveryProbe™ JAK/STAT Compound Library |
|
L1041-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1690 |
|
Description: A unique collection of 109 JAK/STAT inhibitors for JAK/STAT signaling pathway research. |
 DiscoveryProbe? Autophagy Compound Library |
|
L1031-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 13408.8 |
DiscoveryProbe? Autophagy Compound Library |
|
L1031-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 24141.6 |
DiscoveryProbe? Autophagy Compound Library |
|
L1031-5 |
ApexBio |
5 mg/well |
EUR 31380 |
 DiscoveryProbe? Apoptosis Compound Library |
|
L1036-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 4166.4 |
DiscoveryProbe? Apoptosis Compound Library |
|
L1036-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 7437.6 |
DiscoveryProbe? Apoptosis Compound Library |
|
L1036-5 |
ApexBio |
5 mg/well |
EUR 9664.8 |
 DiscoveryProbe™ Stem Cell Compound Library |
|
L1040-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 2970 |
|
Description: A unique collection of 169 stem cell-related compounds for stem cell research. |
 DiscoveryProbe? Ion Channel Compound Library |
|
L1030-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 6672 |
DiscoveryProbe? Ion Channel Compound Library |
|
L1030-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 11863.2 |
DiscoveryProbe? Ion Channel Compound Library |
|
L1030-5 |
ApexBio |
5 mg/well |
EUR 15482.4 |
 DiscoveryProbe™ Bioactive Compound Library Plus |
|
L1022P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 22369 |
|
Description: 5072 bioactive compounds |
DiscoveryProbe™ Bioactive Compound Library Plus |
|
L1022P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 27961 |
|
Description: 5072 bioactive compounds |
DiscoveryProbe™ Bioactive Compound Library Plus |
|
L1022P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 49928 |
|
Description: 5072 bioactive compounds |
 DiscoveryProbe™ Metabolism-related Compound Library Plus |
|
L1032P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 19210 |
|
Description: A unique collection of 2065 metabolism-related compounds for metabolism research. |
DiscoveryProbe™ Metabolism-related Compound Library Plus |
|
L1032P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 24009 |
|
Description: A unique collection of 2065 metabolism-related compounds for metabolism research. |
DiscoveryProbe™ Metabolism-related Compound Library Plus |
|
L1032P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 43134 |
|
Description: A unique collection of 2065 metabolism-related compounds for metabolism research. |
 DiscoveryProbe? Epigenetics Compound Library |
|
L1029-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 7144.8 |
DiscoveryProbe? Epigenetics Compound Library |
|
L1029-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 12866.4 |
DiscoveryProbe? Epigenetics Compound Library |
|
L1029-5 |
ApexBio |
5 mg/well |
EUR 16764 |
 DiscoveryProbe? PI3K/Akt/mTOR Compound Library |
|
L1034-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 4500 |
DiscoveryProbe? PI3K/Akt/mTOR Compound Library |
|
L1034-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 7994.4 |
DiscoveryProbe? PI3K/Akt/mTOR Compound Library |
|
L1034-5 |
ApexBio |
5 mg/well |
EUR 10360.8 |
 DiscoveryProbe™ Autophagy Compound Library |
|
L1031-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 7670 |
|
Description: A unique collection of 486 autophagy-related compounds for autophagy research. |
 DiscoveryProbe™ Apoptosis Compound Library |
|
L1036-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 8690 |
|
Description: A unique collection of 643 apoptosis-related compounds for apoptosis research. |
 DiscoveryProbe™ Ion Channel Compound Library |
|
L1030-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 3800 |
|
Description: A unique collection of 199 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). |
 DiscoveryProbe™ PI3K/Akt/mTOR Compound Library |
|
L1034-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 2750 |
|
Description: A unique collection of 178 PI3K/Akt/mTOR inhibitors for PI3K/Akt/mTOR signaling pathway research. |
 DiscoveryProbe? TGF-beta/Smad Compound Library |
|
L1045-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 1966.8 |
DiscoveryProbe? TGF-beta/Smad Compound Library |
|
L1045-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 3456 |
DiscoveryProbe? TGF-beta/Smad Compound Library |
|
L1045-5 |
ApexBio |
5 mg/well |
EUR 4500 |
 DiscoveryProbe™ Anti-Virus Compound Library |
|
L1050-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 5206 |
|
Description: A collection of 509 Anti-Virus compounds supplied as lyophilized powder or pre-dissolved DMSO solutions |
DiscoveryProbe™ Anti-Virus Compound Library |
|
L1050-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 6517 |
|
Description: A collection of 509 Anti-Virus compounds supplied as lyophilized powder or pre-dissolved DMSO solutions |
DiscoveryProbe™ Anti-Virus Compound Library |
|
L1050-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 11722 |
|
Description: A collection of 509 Anti-Virus compounds supplied as lyophilized powder or pre-dissolved DMSO solutions |
 DiscoveryProbe™ Epigenetics Compound Library |
|
L1029-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4510 |
|
Description: A unique collection of 328 epigenetics-related small molecules for epigenetics reasearch. |
 DiscoveryProbe™ Stem Cell Compound Library Plus |
|
L1040P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4670 |
|
Description: A unique collection of 280 stem cell-related compounds for stem cell research. |
DiscoveryProbe™ Stem Cell Compound Library Plus |
|
L1040P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 5840 |
|
Description: A unique collection of 280 stem cell-related compounds for stem cell research. |
DiscoveryProbe™ Stem Cell Compound Library Plus |
|
L1040P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 10540 |
|
Description: A unique collection of 280 stem cell-related compounds for stem cell research. |
 DiscoveryProbe? Anti-diabetic Compound Library |
|
L1046-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 866.4 |
DiscoveryProbe? Anti-diabetic Compound Library |
|
L1046-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 1507.2 |
DiscoveryProbe? Anti-diabetic Compound Library |
|
L1046-5 |
ApexBio |
5 mg/well |
EUR 1939.2 |
 DiscoveryProbe™ TGF-beta/Smad Compound Library |
|
L1045-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1350 |
|
Description: A unique collection of 88 TGF-beta/Smad inhibitors for TGF-beta/Smad signaling pathway research. |
 DiscoveryProbe™ Autophagy Compound Library Plus |
|
L1031P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 12550 |
|
Description: A unique collection of 837 autophagy-related compounds for autophagy research. |
DiscoveryProbe™ Autophagy Compound Library Plus |
|
L1031P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 15690 |
|
Description: A unique collection of 837 autophagy-related compounds for autophagy research. |
DiscoveryProbe™ Autophagy Compound Library Plus |
|
L1031P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 28300 |
|
Description: A unique collection of 837 autophagy-related compounds for autophagy research. |
 DiscoveryProbe? Anti-infection Compound Library |
|
L1027-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 8439.6 |
DiscoveryProbe? Anti-infection Compound Library |
|
L1027-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 15093.6 |
DiscoveryProbe? Anti-infection Compound Library |
|
L1027-5 |
ApexBio |
5 mg/well |
EUR 19548 |
 DiscoveryProbe™ Ion Channel Compound Library Plus |
|
L1030P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 6020 |
|
Description: A unique collection of 350 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). |
DiscoveryProbe™ Ion Channel Compound Library Plus |
|
L1030P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 7520 |
|
Description: A unique collection of 350 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). |
DiscoveryProbe™ Ion Channel Compound Library Plus |
|
L1030P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 13420 |
|
Description: A unique collection of 350 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). |
 DiscoveryProbe™ Anti-diabetic Compound Library |
|
L1046-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1580 |
|
Description: A unique collection of 110 anti-diabetic small molecule compounds for diabetes research. |
 DiscoveryProbe™ Ubiquitination Compound Library |
|
L1049-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1920 |
|
Description: A collection of 144 ubiquitination compounds supplied as lyophilized powder or pre-dissolved DMSO solutions |
 DiscoveryProbe™ Anti-infection Compound Library |
|
L1027-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4820 |
|
Description: A unique collection of 367 anti-infection small molecules for anti-infection reasearch. |
 DiscoveryProbe™ NF-κB Signaling Compound Library Plus |
|
L1044P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 2340 |
|
Description: A unique collection of 178 NF-κB inhibitors for NF-κB signaling pathway research. |
DiscoveryProbe™ NF-κB Signaling Compound Library Plus |
|
L1044P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 2920 |
|
Description: A unique collection of 178 NF-κB inhibitors for NF-κB signaling pathway research. |
DiscoveryProbe™ NF-κB Signaling Compound Library Plus |
|
L1044P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 5240 |
|
Description: A unique collection of 178 NF-κB inhibitors for NF-κB signaling pathway research. |
 DiscoveryProbe™ Anti-infection Compound Library Plus |
|
L1027P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 12508 |
|
Description: A unique collection of 1004 anti-infection small molecules for anti-infection reasearch. |
DiscoveryProbe™ Anti-infection Compound Library Plus |
|
L1027P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 15643 |
|
Description: A unique collection of 1004 anti-infection small molecules for anti-infection reasearch. |
DiscoveryProbe™ Anti-infection Compound Library Plus |
|
L1027P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 28061 |
|
Description: A unique collection of 1004 anti-infection small molecules for anti-infection reasearch. |
 DiscoveryProbe? Immunology/Inflammation Compound Library |
|
L1042-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 4068 |
DiscoveryProbe? Immunology/Inflammation Compound Library |
|
L1042-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 7298.4 |
DiscoveryProbe? Immunology/Inflammation Compound Library |
|
L1042-5 |
ApexBio |
5 mg/well |
EUR 9525.6 |
 DiscoveryProbe™ Medicine Food Homology Compound Library |
|
L1053-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4210 |
|
Description: 282 Medicine Food Homology compounds |
DiscoveryProbe™ Medicine Food Homology Compound Library |
|
L1053-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 5260 |
|
Description: 282 Medicine Food Homology compounds |
DiscoveryProbe™ Medicine Food Homology Compound Library |
|
L1053-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 9490 |
|
Description: 282 Medicine Food Homology compounds |
 DiscoveryProbe™ Neuronal Signaling Compound Library Plus |
|
L1026P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4570 |
|
Description: A unique collection of 948 neuronal signaling-related small molecules for neuroscience reasearch. |
DiscoveryProbe™ Neuronal Signaling Compound Library Plus |
|
L1026P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 5710 |
|
Description: A unique collection of 948 neuronal signaling-related small molecules for neuroscience reasearch. |
DiscoveryProbe™ Neuronal Signaling Compound Library Plus |
|
L1026P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 10230 |
|
Description: A unique collection of 948 neuronal signaling-related small molecules for neuroscience reasearch. |
 DiscoveryProbe™ Immunology/Inflammation Compound Library |
|
L1042-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 2300 |
|
Description: A unique collection of 295 small molecule compounds for immunology/inflammation research. |
 DiscoveryProbe™ Immunology/Inflammation Compound Library Plus |
|
L1042P-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4900 |
|
Description: A unique collection of 806 small molecule compounds for immunology/inflammation research. |
DiscoveryProbe™ Immunology/Inflammation Compound Library Plus |
|
L1042P-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 6130 |
|
Description: A unique collection of 806 small molecule compounds for immunology/inflammation research. |
DiscoveryProbe™ Immunology/Inflammation Compound Library Plus |
|
L1042P-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 11080 |
|
Description: A unique collection of 806 small molecule compounds for immunology/inflammation research. |
 DiscoveryProbe™ Human Endogenous Metabolite Compound Library |
|
L1051-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 4820 |
|
Description: A collection of 548 Human Endogenous Metabolite Compound supplied as lyophilized powder or pre-dissolved DMSO solutions |
DiscoveryProbe™ Human Endogenous Metabolite Compound Library |
|
L1051-.1 |
ApexBio |
100uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 6030 |
|
Description: A collection of 548 Human Endogenous Metabolite Compound supplied as lyophilized powder or pre-dissolved DMSO solutions |
DiscoveryProbe™ Human Endogenous Metabolite Compound Library |
|
L1051-.25 |
ApexBio |
250uL/well(10 mM solution),96 Well Racks With Screw Cap |
EUR 10840 |
|
Description: A collection of 548 Human Endogenous Metabolite Compound supplied as lyophilized powder or pre-dissolved DMSO solutions |
 DiscoveryProbe? Inhibitor Library |
|
L1048-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 17264.4 |
DiscoveryProbe? Inhibitor Library |
|
L1048-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 30962.4 |
DiscoveryProbe? Inhibitor Library |
|
L1048-5 |
ApexBio |
5 mg/well |
EUR 40288.8 |
 DiscoveryProbe? Cell Cycle Library |
|
L1037-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 2078.4 |
DiscoveryProbe? Cell Cycle Library |
|
L1037-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 3664.8 |
DiscoveryProbe? Cell Cycle Library |
|
L1037-5 |
ApexBio |
5 mg/well |
EUR 4778.4 |
 DiscoveryProbe? Angiogenesis Library |
|
L1047-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 922.8 |
DiscoveryProbe? Angiogenesis Library |
|
L1047-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 1618.8 |
DiscoveryProbe? Angiogenesis Library |
|
L1047-5 |
ApexBio |
5 mg/well |
EUR 2091.6 |
 DiscoveryProbe™ Inhibitor Library |
|
L1048-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 11330 |
|
Description: A unique collection of 2525 inhibitors for high throughput screening (HTS) and high content screening (HCS). |
 DiscoveryProbe™ Cell Cycle Library |
|
L1037-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 3940 |
|
Description: A unique collection of 449 cell cycle-related compounds for cell cycle research. |
 DiscoveryProbe? MAPK Inhibitor Library |
|
L1043-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 2384.4 |
DiscoveryProbe? MAPK Inhibitor Library |
|
L1043-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 4249.2 |
DiscoveryProbe? MAPK Inhibitor Library |
|
L1043-5 |
ApexBio |
5 mg/well |
EUR 5488.8 |
 DiscoveryProbe? NF-?B Signaling Library |
|
L1044-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 1730.4 |
DiscoveryProbe? NF-?B Signaling Library |
|
L1044-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 3052.8 |
DiscoveryProbe? NF-?B Signaling Library |
|
L1044-5 |
ApexBio |
5 mg/well |
EUR 3970.8 |
 DiscoveryProbe? Natural Product Library |
|
L1039-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 5529.6 |
DiscoveryProbe? Natural Product Library |
|
L1039-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 9943.2 |
DiscoveryProbe? Natural Product Library |
|
L1039-5 |
ApexBio |
5 mg/well |
EUR 12866.4 |
 DiscoveryProbe™ Angiogenesis Library |
|
L1047-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1090 |
|
Description: A unique collection of 84 small molecule compounds for angiogenesis research. |
 DiscoveryProbe? Kinase Inhibitor Library |
|
L1024-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 7520.4 |
DiscoveryProbe? Kinase Inhibitor Library |
|
L1024-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 13394.4 |
DiscoveryProbe? Kinase Inhibitor Library |
|
L1024-5 |
ApexBio |
5 mg/well |
EUR 17473.2 |
 DiscoveryProbe™ MAPK Inhibitor Library |
|
L1043-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 1650 |
|
Description: A unique collection of 117 MAPK inhibitors for MAPK signaling pathway research. |
 DiscoveryProbe? Neuronal Signaling Library |
|
L1026-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 5961.6 |
DiscoveryProbe? Neuronal Signaling Library |
|
L1026-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 10639.2 |
DiscoveryProbe? Neuronal Signaling Library |
|
L1026-5 |
ApexBio |
5 mg/well |
EUR 13840.8 |
 DiscoveryProbe? Protease Inhibitor Library |
|
L1035-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 4068 |
DiscoveryProbe? Protease Inhibitor Library |
|
L1035-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 7214.4 |
DiscoveryProbe? Protease Inhibitor Library |
|
L1035-5 |
ApexBio |
5 mg/well |
EUR 9414 |
 DiscoveryProbe™ Natural Product Library |
|
L1039-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 3140 |
|
Description: A unique collection of 550 natural products for high throughput screening (HTS) and high content screening (HCS). |
 DiscoveryProbe? FDA-approved Drug Library |
|
L1021-.1 |
ApexBio |
100 uL/well(10 mM solution) |
EUR 6811.2 |
|
Description: DiscoveryProbe? FDA-approved drug library includes 1496 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. |
DiscoveryProbe? FDA-approved Drug Library |
|
L1021-.25 |
ApexBio |
250 uL/well(10 mM solution) |
EUR 12170.4 |
|
Description: DiscoveryProbe? FDA-approved drug library includes 1496 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. |
DiscoveryProbe? FDA-approved Drug Library |
|
L1021-0.05 |
ApexBio |
50 uL/well(10 mM solution) |
EUR 4514.4 |
|
Description: DiscoveryProbe? FDA-approved drug library includes 1496 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. |
DiscoveryProbe? FDA-approved Drug Library |
|
L1021-5 |
ApexBio |
5 mg/well |
EUR 15789.6 |
|
Description: DiscoveryProbe? FDA-approved drug library includes 1496 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. |
 DiscoveryProbe™ Kinase Inhibitor Library |
|
L1024-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 6650 |
|
Description: A unique collection of 796 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS). |
 DiscoveryProbe™ NF-κB Signaling Library |
|
L1044-.096 |
ApexBio |
100uL/well(10 mM solution),96 Well Deep Well Plate |
EUR 960 |
|
Description: A unique collection of 73 NF-κB inhibitors for NF-κB signaling pathway research. |
Transferring ahead, incorporation of genetic assessments can present extra correct data to information scientific decision-making and predict prognosis amongst sufferers with liver metastases. The scientific applicability of digital next-generation sequencing (dNGS), which eliminates polymerase chain response (PCR) and sequencing error-derived noise through the use of molecular barcodes (MBs), has not been absolutely evaluated. We evaluated the utility of dNGS of cell-free DNA (cfDNA) in liquid biopsies obtained from sufferers with pancreatic most cancers.
